We have employed Crashplan <http://www11.crashplan.com/business/> at my organization with great success over the last several months. Backup and restore are pretty straightforward, and as mentioned by someone else, the ability to “seed” backups to a local location before backing up over WAN is pretty awesome. A neat thing about it too, is that it will back up in the background while a user is working, w/out the actual client app having to be open.
If you do end up using it, I recommend QOS’ing your network traffic to limit Crashplan to an acceptable bandwidth max so it doesn’t eat up your whole pipe with those potentially huge initial full backups – and if possible, set up a few backup servers/locations so you can sort of load balance…
Every single laptop in our company is “Crashplanned” and it has worked out pretty great.
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