Not sure if anyone's had much experience with Adobe apps running on an Xsan volume but they appear to be pretty flakey. Had a look at what's going on and it *may* be the fact that Xsan doesn't support exchangedata(2) which would make sense with the amount of data things like Illustrator in particular put in resource forks.
Symptoms vary but mainly seem to be gradual file corruption. Anyone know any way to work around this?